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Updated: Jan 18, 2026

In Vivo Immunogenicity Screening of Tumor-Derived Extracellular Vesicles by Flow Cytometry of Splenic T Cells
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塔加维文特触发了TECR依赖的非瘤癌细胞死亡

Logan Leak1, Ziwei Wang2, Alby J Joseph1

  • 1Department of Biology, Stanford University, Stanford, CA, USA.

Nature chemical biology
|May 26, 2025
PubMed
概括

一种候选药物Tegavivint在癌细胞中触发了一种新型的非apoptotic细胞死亡途径. 这种机制依赖于脂质酶转-2,3--CoA减少酶 (TECR),与已知的细胞死亡类型不同.

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