相关实验视频

Updated: Sep 20, 2025

Glutamate and Hypoxia as a Stress Model for the Isolated Perfused Vertebrate Retina

Glutamate and Hypoxia as a Stress Model for the Isolated Perfused Vertebrate Retina

Published on: March 22, 2015

全球研究趋势2000年至2024年视网膜疾病中的内质网膜应激

Weiwen Hu¹, Yahan Tu², Jian Tan³

¹Department of Ophthalmology, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, People's Republic of China.

International ophthalmology

|May 26, 2025

概括

在视网膜疾病中对内质网膜应激 (ERS) 的全球研究激增,揭示了关键趋势和治疗目标. 这项分析强调了ERS作为理解和治疗视网膜疾病的关键领域.

科学领域:

眼科和视觉科学眼科和视觉科学
分子生物学分子生物学
细胞生物学细胞生物学

背景情况:

细胞内膜网膜应激 (ERS) 与各种视网膜病理有关.
了解ERS和视网膜疾病的全球研究趋势对于推进治疗策略至关重要.

研究的目的:

在视网膜疾病中对内质网膜应激 (ERS) 的全球研究进行全面的文献分析.
在过去24年中,确定这一领域的关键研究趋势,有影响力的作者,机构和期刊.

主要方法:

从科学网络核心收藏 (2000-2024) 中对917篇出版物的图书统计分析.
利用图书识别和可视化软件来识别研究模式和关键贡献者.
分析了作者关键词,以确定主要的研究主题和引文爆发.

主要成果:

美国在出版物和引用方面处于领先地位,其中海德阿基·哈拉和莎拉·X·张作为顶级作者.
关键的研究主题包括光受体退化,玻璃眼,糖尿病视网膜病变和与年龄相关的黄斑退化.
研究已经从神经保护发展到专注于特定的细胞类型,信号通路,分子洞察力和基因治疗.

结论:

对视网膜疾病的ERS研究显著增长表明学术兴趣日益增加.
对于视网膜神经微血管和相关疾病来说,ERS是一种有前途的治疗标.
需要进一步研究ESR机制和在视网膜疾病中的治疗应用.

关键词:

图书统计学分析糖尿病视网膜病变 - 糖尿病视网膜病变细胞内膜网膜应激压力研究趋势研究趋势视网膜疾病视网膜疾病

更多相关视频

Real-Time Analysis of Bioenergetics in Primary Human Retinal Pigment Epithelial Cells Using High-Resolution Respirometry

Real-Time Analysis of Bioenergetics in Primary Human Retinal Pigment Epithelial Cells Using High-Resolution Respirometry

Published on: February 3, 2023

Isolation of Retinal Pigment Epithelial Cells from Guinea Pig Eyes

Isolation of Retinal Pigment Epithelial Cells from Guinea Pig Eyes

Published on: May 9, 2023

相关概念视频

Role of ER in the Secretory Pathway

Role of ER in the Secretory Pathway

Eukaryotic cells have a special pathway that enables communication between various intracellular membrane-bound compartments and also with the extracellular environment. This pathway is termed as the secretory pathway.
Components of the secretory pathway
About a third of proteins synthesized in the cell are sorted via the secretory route. They shuffle between different compartments in membrane-bound vesicles until they reach their final destination. The main intracellular compartments involved...