对肝细胞癌与门静脉血栓的重复超选择性透导管动脉化学栓塞
Akira Yamamoto1, Ken Kageyama1, Atsushi Jogo1
1Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, Osaka 545-8585, Japan.
The British journal of radiology
|May 26, 2025
概括
重复超选择性跨动脉化学栓塞 (rusTACE) 是对肝细胞癌 (HCC) 与门静脉瘤血栓 (PVTT) 的安全有效治疗方法. 这种方法表明,在选定的患者中,完全响应率高,长期存活率改善.
科学领域:
- 干预性放射学 干预性放射学
- 肝胆瘤学 肝胆瘤学
- 血管干预 血管干预
背景情况:
- 肝细胞癌 (HCC) 与门静脉瘤血栓 (PVTT) 构成一个重大的临床挑战.
- 现有的PVTTHCC治疗方法在有效性和安全性方面存在局限性.
研究的目的:
- 为了评估重复超选择性跨动脉化学栓塞 (rusTACE) 的安全性和长期有效性,使用1.7-Fr-tip微导管.
- 在被诊断为HCC和PVTT的患者中评估rusTACE.
主要方法:
- 用rusTACE治疗的PVTTHCC患者的回顾性分析 (2014年5月 - 2022年7月).
- 使用1.7-Fr-tip微导管进行瘤食动脉的超选择性栓塞.
- 在2个月内至少两次重复治疗,评估治疗反应,存活率,不良事件和肝功能.
主要成果:
- 在20名患者中,rusTACE的耐受性很好,平均存活时间为26.1个月.
- 实现了PVTT的75%完整响应 (CR) 率,在整个随访期间保持了35%的CR.
- 确定的预后因素包括查尔德-普格评分,PVTT和全身瘤的CR,以及肝脏瘤负担.
结论:
- rusTACE是一种安全有效的治疗PVTT的HCC在选定的Child-Pugh类A患者.
- 该程序显示了高CR率和有利的整体存活率.
- 短期治疗间隔和超选择性栓塞有助于积极的结果.
更多相关视频
09:49Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization
Published on: December 2, 2013
10.4K
08:45New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation
Published on: June 27, 2025
758
相关概念视频
01:21Hepatic Portal System
2.4K
The hepatic portal system, a critical part of our circulatory framework, transports nutrient-laden, deoxygenated blood from the gastrointestinal tract and spleen to the liver. This ingenious system plays an indispensable role in maintaining our body's metabolic equilibrium.
At its core, the hepatic portal vein is the result of a confluence of the superior and inferior mesenteric veins along with the splenic vein. Each of these veins has a unique role. The superior mesenteric vein is...
At its core, the hepatic portal vein is the result of a confluence of the superior and inferior mesenteric veins along with the splenic vein. Each of these veins has a unique role. The superior mesenteric vein is...
2.4K
01:29Venous Thrombosis III: Interprofessional Care
29
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
29
01:29Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
48
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
48