在患有 status epilepticus 重复发作的儿科患者治疗的时间
Jennifer V Gettings1, Iván Sánchez Fernández1,2, Anne Anderson3
1Division of Epilepsy and Clinical Neurophysiology, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
患有重复状态发作的儿科患者在随后的发作中没有改善治疗时间. 以前的诊断是复发的唯一预测因素,强调需要更好的干预措施和护理人员教育.
科学领域:
- 神经学 神经学
- 儿科症 儿科症
背景情况:
- 状态 (SE) 是儿童的神经紧急情况.
- 了解预测经常性SE的因素对于及时干预至关重要.
研究的目的:
- 为了比较儿科患者的临床因素,复发性SE与单次SE发作相比.
- 为了确定儿童重复状态的预测因素.
主要方法:
- 一个多中心的回顾性分析,前性观察队列.
- 从2011年到2019年包括患有 status epilepticus 的儿科患者.
主要成果:
- 10.3%的患者经历了复发性状态.
- 之前的诊断是SE复发的唯一预测因素.
- 对于第一个和第二次SE发作来说,对佐地亚zepine或非佐地亚zepine抗发作药物治疗的时间没有显著差异.
- 医院外SE的护理人员治疗在第一和第二次发作之间没有改善,尽管当护理人员管理时,二zepine的时间更快.
结论:
- 儿童复发性状态的治疗时间没有改善.
- 有机会加强护理人员教育和儿童SE的干预策略.
- 之前的诊断是与复发性状态相关的关键因素.
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