超三角囊切除术:用于治疗辐射引起的出血性囊炎的最后一线治疗
José Alberto Pereira1, Duarte Vieira-Brito2, Mário Lourenço3
1Urology Department, Portuguese Institute of Oncology, Coimbra. joseaclpereira@gmail.com.
概括
超三角囊切除术为辐射诱导的出血性囊炎提供了可行的最后手段治疗,在之前接受骨盆辐射治疗的患者中显示出良好的生存率和可管理的并发症.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 手术瘤学手术瘤学
背景情况:
- 出血性囊炎 (HC) 是患有恶性瘤的盆腔放射治疗后的一个常见并发症.
- 它呈现出血和下泌尿道症状,往往不耐保守管理.
- 治疗的挑战包括患者的并发症和对耐火病例缺乏明确的指导方针.
研究的目的:
- 评估超三角囊切除术与尿路转移的疗效和安全性,作为辐射诱导出血囊炎的最后一线治疗方法.
- 为这种特殊的外科手术方法提供机构成果.
主要方法:
- 一项对17名患者的回顾性分析,这些患者接受了 supratrigonal 囊切除术和膀粘膜充血,尿路转移以治疗耐火性辐射诱导的HC.
- 从2010年1月到2020年12月收集的数据.
主要成果:
- 这项研究包括17名患者 (64.7%为女性,中位数年龄为69岁),HC主要是由于妇科癌症辐射.
- 大多数患者先前接受过治疗,包括膀灌,充血,有些人接受了静脉内甲或高压氧气疗法.
- 术后并发症 (Clavien-Dindo III级或更高) 在29.4%的患者中发生,平均住院时间为12天.
- 没有报告30天死亡率,随访时间中位数为28个月,具有高的1年和3年生存率 (分别为93.3%和83.3%).
结论:
- 用尿路转移进行超三角囊切除术是一种有效和有效的最后一线治疗辐射诱导出血性囊炎的选择.
- 与简单的囊切除术相比,这种手术可以降低患有广泛的盆腔辐射的患者的风险.
- 无论采用哪种类型的尿路转移,结果都是有利的.
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