头骨底部骨髓炎 - 微生物特征和管理影响
Katti Blessi Sara1, Zachariah Thomas1, P Lokesh Kumar2
1Department of Otorhinolaryngology, Christian Medical College, Vellore, Tamilnadu 632004 India.
概括
头骨底部骨髓炎 (SBO) 是一种严重的感染. 通过向活检和培养特异性抗生素的早期诊断显著改善了患有这种危险疾病的患者的结果.
科学领域:
- 传染性疾病 传染性疾病
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经外科 神经外科
背景情况:
- 头骨底部骨质炎 (SBO) 是一种高发病率和死亡率的危及生命的感染.
- 常见的来源包括otogenic,rhinogenic和odontogenic来源.
- 关键症状包括严重的夜间疼痛和神经.
研究的目的:
- 对134名SBO患者的人口,临床,外科和微生物学数据进行回顾性分析.
- 评估针对性活检,脱bridement和培养特异性抗生素治疗的有效性.
主要方法:
- 从134名SBO患者的临床数据的回顾性审查.
- 对人口统计细节,临床特征,外科手术和微生物学资料的分析.
- 123名患者接受了有针对性的活检和脱bridement.
主要成果:
- 队列中男性占优势,平均年龄为60岁,平均HbA1C为8.4 (不受控制的糖尿病).
- 严重的耳痛和面部神经麻是最常见的症状.
- 培养阳性率为85.4%,其中包括Pseudomonas,Aspergillus和Staphylococcus spp. 作为常见的病原体.
- 针对性活检,脱bridement和培养特异性抗生素观察到85%的临床改善.
结论:
- SBO是一种严重的细菌或真菌感染,需要早期诊断.
- 有针对性的活检可以达到高的培养阳性率 (84.6%).
- 长期,培养特定的抗生素/抗真菌治疗导致改善临床结果.
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