治疗癌症患者疲劳的
Sarah Messer1, Annika Oeser1, Carina Wagner1
1Cochrane Haematology, Cochrane ESU Germany/UK, Institute of Public Health, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
The Cochrane database of systematic reviews
|May 27, 2025
概括
可以帮助减少与癌症相关的疲劳 (CRF),并改善癌症患者的生活质量 (QoL),特别是在治疗后. 然而,这些证据是不确定的,强调需要对进行更严格的研究.
科学领域:
- 在瘤学瘤学.
- 综合医学是一个整体的医学.
- 基于证据的实践.
背景情况:
- 癌症相关疲劳 (CRF) 是影响癌症患者生活质量的普遍症状.
- 运动干预措施对管理CRF有希望,但对的长期影响的具体证据仍然有限.
- 本综述是研究运动在控制与癌症相关的疲劳中的作用系列的一部分.
研究的目的:
- 评估对癌症相关疲劳 (CRF) 和癌症患者的生活质量 (QoL) 的影响.
- 评估不同治疗阶段 (之前,期间,之后) 和时间框架 (短期,中期,长期) 的结果.
- 检查对不良事件,抑郁和焦虑的影响.
主要方法:
- 随机对照试验 (RCT) 的系统审查和元分析.
- 搜索了多个数据库直到2023年10月,包括CENTRAL,MEDLINE和Embase.
- 包括对任何癌症类型的成年人进行和没有的RCT,每组至少有五次面对面的课程和20名参与者.
主要成果:
- 抗癌治疗后的可能会减少短期的CRF (中度确定性证据).
- 治疗期间对CRF和QoL的影响的证据非常不确定 (非常低的确定性证据).
- 对于长期CRF和QoL结果以及治疗前开始的数据有限.
结论:
- 目前关于在癌症治疗期间或之后管理CRF和QoL的好处的证据尚不确定.
- 虽然显示出潜力,但由于证据的局限性,建议谨慎实施.
- 未来的RCT需要严格的方法,适当的样本大小和适当的控制来澄清的作用.
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