开发一种个性化的方法来跟踪血细胞培养在格兰阴性血流感染:一个叙事审查
Renatos-Nikolaos Tziolos1, Diamantis P Kofteridis1
1Department of Internal Medicine and Infectious Diseases, University of Crete, Medical School, University Hospital of Heraklion, 71500 Heraklion, Crete, Greece.
Diseases (Basel, Switzerland)
|May 27, 2025
概括
随访血培养 (FUBCs) 对于格拉姆阴性血流感染 (GN-BSIs) 在不复杂的情况下往往缺乏实用性. 具有特定风险因素的选定患者可能会受益,这需要进一步研究.
科学领域:
- 传染性疾病 传染性疾病
- 临床微生物学 临床微生物学
- 内部医学 内部医学
背景情况:
- 随访血液培养 (FUBCs) 在格拉姆阴性血流感染 (GN-BSIs) 的临床实用性受到争议.
- 缺乏指导方针导致过度使用,增加医疗保健成本和抗生素暴露.
研究的目的:
- 审查GN-BSI中FUBCs的证据.
- 为FUBC利用提供个性化的方法.
主要方法:
- 对GN-BSI中FUBCs的现有文献进行系统审查和批判性评估.
- 对影响FUBC结果的研究方法和患者特征的分析.
主要成果:
- 在不复杂的GN-BSI中,FUBC显示持久阳性培养的低产量.
- 在一般人群中没有观察到对死亡率的显著影响.
- 在选定的患者中发现了潜在的益处,包括那些患有内血管感染,中央静脉导管,反应不佳或缺乏源控制的患者.
结论:
- 在不复杂的GN-BSI中,FUBC通常是不必要的.
- 需要采取量身定制的方法,考虑特定的患者因素.
- 随机对照试验对于验证FUBC使用的指示至关重要.
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