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Updated: Sep 20, 2025

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
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Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

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从罕见到常见:在一项多中心西班牙研究中对TLR7变体的遗传洞察力COVID-19严重程度的多中心西班牙研究

Arnau Antolí1,2,3,4, Gardenia Vargas-Parra5,6,7, Angels Sierra-Fortuny1,3

  • 1Internal Medicine Department, Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain.

Journal of clinical immunology
|May 27, 2025
PubMed
概括

收费类受体7 (TLR7) 变体与严重的COVID-19有关. 在严重的COVID-19病例中发现了罕见的TLR7变体,N215S显示功能丧失,影响抗病毒免疫力.

关键词:
在 COVID-19 疫情中,在TLR7中,这是一个X-linked.免疫缺陷是一种免疫缺陷.具有天生的免疫力.

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