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Updated: Sep 20, 2025

An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
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An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment

Published on: December 3, 2020

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在人类小肠壁的微生理学体外模型中,对亲药代谢和药物透性动学的表征,包括产生粘液的细胞,并与LC-MS/MS分析相结合

Sultan K AlShmmari1,2, Roa S Fardous2,3, Mohammed A ALHamamah4

  • 1Leibniz Institute of Photonic Technology, Member of Leibniz Health Technologies, Member of the Leibniz Centre for Photonics in Infection Research (LPI), Albert-Einstein-Straße 9, 07745, Jena, Germany.

Advanced healthcare materials
|May 27, 2025
PubMed
概括

创建了一个人类小肠的新型微流体模型,包括产生粘液的细胞. 这种模型准确地模拟了药物吸收和前药物代谢,揭示了粘液.

关键词:
在 LC-MS/MS 中使用.在体外模型模型中的体外模型.这是粘液粘液.药物动力学 药物动力学支持毒品的支持者.小肠小肠的小肠的小肠.

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