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Updated: Sep 20, 2025

Synthesis of Masarimycin, a Small Molecule Inhibitor of Gram-Positive Bacterial Growth
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阳离子和酸盐抑制了LsAA9A,一种性多糖胺单氧化酶 (LPMO)

Valerio Di Domenico1, Yusuf Theibich1, Søren Brander2

  • 1Department of Chemistry, University of Copenhagen, Denmark.

The FEBS journal
|May 27, 2025
PubMed
概括

离子抑制了多糖单氧酶 (LPMO) 的活性,而酸盐与活性部位的结合阻断了基质的接入. 研究人员应避免在LPMO研究中使用酸盐,以防止铜抽象和基质竞争.

关键词:
在X射线晶体学.辅助活动是辅助活动.生物质的生物质是生物质.碳水化合物活性酶的活性酶.抑制剂抑制剂的使用

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