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Updated: Jun 12, 2025

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替代cGAS信号传输促进了简单疹脑炎

Liraz Shmuel-Galia1, Zhaozhao Jiang1, Laurel Stine1

  • 1Division of Innate Immunity, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA 01605.

Proceedings of the National Academy of Sciences of the United States of America
|May 27, 2025
PubMed
概括

循环GMP-AMP合成酶 (cGAS) 有一个新发现的信号通路,独立于cGAMP. 这种替代途径增强了CXCL1的表达和中性粒细胞的招募,影响病毒感染.

关键词:
在HSV中,它是HSV.cGAS 是一个气体.感染感染的感染.鼠标模型 鼠标模型鼠标模型第一种类型的IFN IFN.

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