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Updated: Sep 20, 2025

Generation of In-Frame Gene Deletion Mutants in Pseudomonas aeruginosa and Testing for Virulence Attenuation in a Simple Mouse Model of Infection
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Generation of In-Frame Gene Deletion Mutants in Pseudomonas aeruginosa and Testing for Virulence Attenuation in a Simple Mouse Model of Infection

Published on: January 8, 2020

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聚亚丁酶PAPI是需要在致病性细菌中维护毒性等离子体的

Katherine Schubert1, Jessica Zhang2,3, Michele E Muscolo4,5

  • 1Department of Molecular, Cell, and Developmental Biology, UC Santa Cruz, Santa Cruz, California, United States of America.

PLoS pathogens
|May 27, 2025
PubMed
概括

染色体基因pcnB,编码多基酶PAP I,对于维持Yersinia和Shigella病原体中的毒性质粒至关重要. 这种基因稳定了等离子体,增强了抗生素耐药性,并增强了细菌的毒性.

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