在新诊断的2型糖尿病患者中,身体构成参数与大动脉弹性属性的关联
Turgut Karabag1, Işil Isel2, Sena Hekimoglu Ustabas2
1Saglik Bilimleri University, Istanbul Education and Research Hospital, Department of Cardiology.
概括
新诊断的2型糖尿病 (T2DM) 损害了大动脉弹性功能. 三重体质指数 (TMI) 显示出最强的关联,表明其作为T2DM患者血管健康查工具的潜力.
科学领域:
- 心血管医学 心血管医学
- 内分泌学 在内分泌学.
- 医疗成像医学成像
背景情况:
- 2型糖尿病 (T2DM) 与大动脉弹性功能和心脏重塑的早期损伤有关.
- 这些血管变化在T2DM诊断时显而易见.
研究的目的:
- 为了研究新诊断的T2DM患者的大动脉弹性功能的改变.
- 探索大动脉弹性特性与各种身体组成参数之间的关联.
主要方法:
- 在273名T2DM患者和139名对照患者中,用于评估大动脉弹性参数的跨胸腔心声学 (TTE).
- 计算了全面的身体组成指数,包括身体质量指数,腰与部比率,三重体质量指数 (TMI) 等.
主要成果:
- 与对照组相比,新诊断的T2DM患者表现出明显较低的大动脉应变和延展性,以及较高的大动脉刚度指数.
- 大动脉弹性参数与大多数身体成分指数显著相关,特别是TMI.
结论:
- 在新诊断的T2DM患者中,大动脉弹性功能受损.
- 三重体质量指数 (TMI) 显示出与大动脉弹性受损的最强相关性,表明其作为动脉样硬化过程的查工具的潜力.
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