儿童瘤学患者进行血造干细胞移植的味道变化:系统性审查和元分析
Eyşan Hanzade Savaş1, Aylin Akça Sümengen2, Ayşe Ay3
1Independent researcher, Suadiye, Halay St., No:7, Istanbul, Türkiye.
Seminars in oncology nursing
|May 27, 2025
概括
血造干细胞移植 (HSCT) 后的儿科患者常见的口味变化. 早期发现和管理对于营养和生活质量至关重要.
科学领域:
- 在瘤学瘤学.
- 血液学 血液学 血液学
- 儿科 儿科 儿科
背景情况:
- 味觉变化是经常发生的,但未被认可的,小儿瘤病患者在血造细胞干细胞移植 (HSCT) 后的副作用.
- 这些感官变化显著影响患者的营养和整体生活质量.
研究的目的:
- 系统地审查和分析关于儿科HSCT患者味觉变化的现有证据.
- 为了确定口味变化的流行率,特征和阶段特定变化.
主要方法:
- 在六个主要的学术数据库中进行了全面的文献搜索.
- 数据提取和质量评估是由两个独立的审查员根据PRISMA指南进行的.
- 该审查已与PROSPERO (ID:CRD42025646761) 进行注册.
主要成果:
- 该分析包括1,403名儿科患者 (年龄为0.4-29.9岁).
- 味道变化,包括食和味道值变化 (尤其是甜味和味),尤其在移植后的早期阶段很普遍.
- 分析显示事件发生率为0.457 (95% CI:0.330-0.590),这在统计学上并不显著 (P=0.529).
结论:
- 味觉变化是儿科HSCT接受者的常见现象,根据治疗阶段和如何评估味道而有所不同.
- 快速识别和有针对性的管理策略对于解决营养缺陷和改善生活质量至关重要.
- 评估工具和干预协议的标准化对于未来的研究是必要的.
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