一种模仿禁食的饮食计划可以减少腹部脂肪组织,同时在2型糖尿病患者中保持腹部肌肉质量
Marjolein P Schoonakker1, Elske L van den Burg1, Petra G van Peet1
1Department of Public Health and Primary Care, Leiden University Medical Center (LUMC), Leiden, the Netherlands.
概括
一个为期12个月的禁食模仿饮食 (FMD) 计划显著减少了2型糖尿病患者的腹部内脏和皮下脂肪组织. 这种饮食干预,以及通常的护理,也改善了代谢参数,如HbA1c.
科学领域:
- 代谢性疾病研究研究.
- 营养科学 营养科学
- 临床干预研究临床干预研究
背景情况:
- 2型糖尿病的管理通常涉及生活方式干预.
- 腹部脂肪是2型糖尿病并发症的关键因素.
- 需要新的饮食策略来改善血糖控制和身体组成.
研究的目的:
- 为了评估仿制禁食饮食 (FMD) 对2型糖尿病患者脂肪组织和肌肉质量的影响.
- 评估口病对腹部内脏脂肪组织 (aVAT) 和皮下脂肪组织 (aSAT) 的影响.
- 为了确定身体组成和代谢参数变化之间的关联.
主要方法:
- 一项随机对照试验,涉及100名2型糖尿病患者.
- 参与者每月接受一次为期5天的口炎加上通常的护理,或者仅仅接受12个月的通常护理.
- 使用MRI测量了腹部脂肪组织和肌肉区域.
主要成果:
- 与对照组相比,口疫组的aVAT (-37.9厘米2) 和aSAT (-20.9厘米2) 显著减少.
- 腹肌区域 (aMA) 没有显著变化.
- aVAT和aSAT的降低与HbA1c和其他代谢标志物的改善密切相关.
结论:
- 一个为期12个月的口疾病计划有效地减少了2型糖尿病患者的腹部内脏和皮下脂肪.
- 口疾病干预表明作为2型糖尿病的辅助治疗的潜力,改善身体组成和代谢健康.
- 在这个人群中,口病显示出改善血糖控制和相关代谢参数的前景.
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