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在FDG-avid甲状腺结节中,恶性瘤的风险显著增加

Brodie D Laurie¹, Elizabeth Thomas², Hieu Nguyen¹

¹Endocrine Surgical Services Unit, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, Australia.

American journal of surgery

|May 27, 2025

概括

偶然发现的FDG-avid甲状腺结节具有高恶性瘤风险,特别是在贝塞斯达III-VI类. 精细针吸收 (FNA) 细胞学对于评估这些潜在的癌症甲状腺意外瘤至关重要.

科学领域:

核医学是一种核医学.
在瘤学瘤学.
内分泌学在内分泌学.

背景情况:

由于潜在的恶性瘤,FDG-avid甲状腺偶发性瘤存在诊断挑战.
根据细针吸收 (FNA) 细胞学评估恶性瘤的发病率至关重要.

研究的目的:

为了确定FDG-avid甲状腺结核中的恶性瘤率.
通过FNA细胞学结果 (贝塞斯达系统) 来分层这些率.
评估恶性瘤的预测因素,包括年龄,性别和结节大小.

主要方法:

对258名为FDG-avid甲状腺意外瘤进行手术切除的患者进行了回顾性队列研究 (2012-2023年).
对与手术前FNA细胞学相关的恶性瘤发病率的分析 (贝塞斯达类别I-VI).
后勤回归用于评估年龄,性别和结节大小作为预测因素.

主要成果:

总体恶性瘤发病率为48.1%,主要是乳头状甲状腺癌.
恶性瘤的发病率因贝塞斯达类别而异:I (15.4%) 到VI (98.3%).
年龄,性别和结节大小并不能显著预测恶性瘤.

结论:

甲状腺FDG活性结节带有明显增加的恶性瘤的风险.
这种风险在贝塞斯达的III至VI类中尤为明显.
FNA细胞学是风险分层的一个关键决定因素.

关键词:

德国联邦航空公司 (FDG)精细针吸入细胞学精细针吸入细胞学甲状腺癌是什么?甲状腺癌是什么?甲状腺偶发性瘤甲状腺结节甲状腺结节

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