内在免疫性是SARS-CoV-2感染中类型特异性反应的主要决定因素

Grace E Quirk1, Marta V Schoenle2,3, Kameron L Peyton2

  • 1Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ, USA.

Nature immunology
|May 27, 2025
PubMed
概括

疫苗免疫力增强了对SARS-CoV-2变体的中和抗体,但对漂移表位体的类型特异性B细胞反应仍然很差. 变异性表位的抗原性较差,而不是先前的免疫力,限制了这些关键的免疫反应.

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