在L3脊椎水平的2DMRI切片上使用DAFS Express进行自动化身体组成分析
Varun Akella1,2, Razeyeh Bagherinasab1, Hyunwoo Lee3
1School of Engineering Science, Simon Fraser University, Vancouver, Canada.
Journal of imaging informatics in medicine
|May 27, 2025
概括
使用DAFS Express的自动化MRI身体组成分析显示了高精度,可与骨肌肉,内脏脂肪组织和皮下脂肪组织的手动细分相美. 该工具简化了分析,以提高临床和研究环境中的诊断效率.
科学领域:
- 医疗成像医学成像
- 放射学 放射学是一门学科.
- 生物医学工程 生物医学工程
背景情况:
- 身体成分分析对于诊断诸如肥胖和肉类症等疾病至关重要.
- 对MRI扫描进行手动细分,以检测身体组成是耗时的,并限制了临床使用.
- 需要自动化工具来提高身体成分分析的效率和准确性.
研究的目的:
- 为了验证自动化工具DAFS Express的准确性和可靠性,用于基于二维MRI的身体组成分析.
- 将骨肌肉 (SM),内脏脂肪组织 (VAT) 和皮下脂肪组织 (SAT) 的自动测量与专家手工细分进行比较.
- 评估DAFS Express在简化临床和研究工作流程方面的潜力.
主要方法:
- 利用了来自399名参与者的英国生物库数据 (423个L3片).
- 达夫斯快递进行了SM,VAT和SAT的自动细分.
- 专家手动细分作为验证的黄金标准.
- 通过Jaccard/Dice分数,ICC和Bland-Altman图表进行评估.
主要成果:
- 自动和手动细分之间的高度一致性 (雅卡德:SM 99.03%,增值税95.25%,SAT 99.57%;子:SM 99.51%,增值税97.41%,SAT 99.78%).
- 具有最小偏差的一致横截面积测量 (SM:自动132.51厘米,手动132.36厘米;增值税:自动137.07厘米,手动134.46厘米;SAT:自动203.39厘米,手动202.85厘米2).
- 强大的可靠性 (ICC:SM 0.998,VAT 0.994,SAT 0.994) 和快速的处理时间 (18s/DICOM).
结论:
- DAFS Express提供精确可靠的自动化细分,用于2DMRI的身体组成分析.
- 该工具显著减少了分析时间,提高了研究和临床环境的效率.
- 建议对各种应用进行进一步验证,以最大限度地提高其临床效用.
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