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甲状腺结节的风险分层诊断为卵泡新生体在核心针检查中

Byeong-Joo Noh¹, Won Jun Kim², Jin Yub Kim²

¹Department of Pathology, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea.

Endocrinology and metabolism (Seoul, Korea)

|May 28, 2025

概括

核心针活检子类别IVb显著改善了对甲状腺结节的恶性瘤风险评估. 这种精细的方法有助于确定适当的管理,减少良性病例不必要的手术.

科学领域:

内分泌学在内分泌学.
在瘤学瘤学.
病理学病理学病理学

背景情况:

被诊断为卵泡瘤 (FN) 的甲状腺结节需要对恶性瘤进行准确的风险分层.
核心针活检 (CNB) 分类为改善诊断性能提供了一种潜在的方法.

研究的目的:

评估CNB分类的风险分层和诊断性能,以评估甲状腺结节中恶性瘤的风险分层和诊断性能,分类为FN.
为了比较CNB子类别对结节大小和超声波风险分层系统 (RSSs) 的有效性.

主要方法:

对313个甲状腺结节 (>1厘米) 的回顾性和前性分析,诊断为CNB上的FN,并进行手术组织学.
基于建筑统一性和核异型的CNB子类别的分类.
对恶性瘤的CNB子类别,结节大小和超声波RSS的诊断性能的评估.

主要成果:

与其他子类别 (4,2%-13,6%) 相比,CNB IVb子类别的恶性瘤风险显著更高 (34.5%-83.7%).
CNB分类IVb是恶性瘤的独立预测指标,其表现优于结节大小和超声波RSS.
CNB IVb 分类对恶性瘤的敏感性更高,对良性结节的不必要手术减少.

结论:

CNB IVb 分类在甲状腺结节中对恶性瘤风险进行分层是有效的,超过了传统方法.
非IVb结节≤3厘米可以通过超声监测来管理,避免立即手术.

关键词:

活检,大核心针头针.甲状腺新生瘤的发生.甲状腺结节甲状腺结节超声波学超声波学超声波学

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