在两个高等教育医院评估新鲜冷血输血的适宜性
Jongmin Kim1, Kae Lyang Koo2, Hyun-Ji Lee1,2,3
1Department of Laboratory Medicine, Pusan National University School of Medicine, Yangsan, South Korea.
Transfusion medicine (Oxford, England)
|May 28, 2025
概括
新鲜冷血 (FFP) 输血往往不合适,其中40.6%未能满足标准. 优化FFP使用需要机构特定的策略来改善输血实践.
科学领域:
- 输血医学 输血医学
- 血液学 血液学 血液学
- 临床病理学 临床病理学
背景情况:
- 尽管有基于证据的指导方针,但新鲜冷血 (FFP) 经常被处方不当.
- 这项研究评估了FFP输血在三级教学医院的适当性.
- 分析的重点是适当和不适当的输血的特征.
研究的目的:
- 评估新鲜冷血 (FFP) 输血的适当性.
- 分析与适当和不适当的FPF使用相关的因素.
- 确定优化血输血实践的领域.
主要方法:
- 从2022年10月至12月的584次初始FFP输血的回顾性分析.
- 评估患者数据,实验室结果 (PT,INR,aPTT) 和输血因素.
- 将FFP输血分为八组,以确定适当性,其次治疗剂量定义为≤2单位.
主要成果:
- 42.1%的FFP输血涉及亚治疗剂量.
- 整体适用率为51.5%,医院的差异很大 (35.3%对73.2%).
- 不适当的输血与更高的INR有关,并与严重出血/手术 (73.4%) 有关.
结论:
- 40.6%的FFP输血是不合适的,因为没有达到实验室标准.
- 适当性的显著差异凸显了针对量身定制的输血协议的需要.
- 机构特定的管理对于优化血输血实践至关重要.
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