在功能性脏移植中产生的尿癌
Oana Moldoveanu1, Cătălin Baston1,2, Bogdan Sorohan2,3
1Department of Urology, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Biomedicines
|May 28, 2025
概括
接受脏移植的人面临癌症风险增加. 一个案例突出了膀癌的成功治疗,随后是转移性全移植癌症,强调需要明确的管理准则.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 移植 移植 移植 移植
背景情况:
- 接受脏移植的人患恶性瘤的风险更高.
- 恶性瘤是该人口中死亡的第三大原因.
- 泌尿癌,特别是在全移植中,是一个令人担忧的问题.
研究的目的:
- 在移植接受者中报告尿癌进展的独特病例.
- 讨论处理这些复杂案件所面临的挑战.
主要方法:
- 一个接受脏移植的病例报告.
- 治疗包括通过尿道切除膀瘤 (TURBT) 和菌卡尔梅特-格林 (BCG) 灌注.
- 随后的治疗包括脏切除术与膀保存,停止免疫疗法,没有全身化疗.
主要成果:
- 最初的非肌肉侵入性膀癌已成功治疗.
- 两年后发生的异种移植的转移性尿路细胞癌.
- 患者在2年的随访中实现了局部瘤控制和肺转移的自发回归.
结论:
- 在移植接受者的尿路癌的管理是具有挑战性的.
- 对于这些患者,缺乏确定的治疗指南或治疗方案.
- 多学科的合作对于最佳的患者结果至关重要.
相关概念视频
Kidney Transplant II: Surgical Procedure
325
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
325
Kidney Transplant I: Introduction
349
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
349
Kidney Transplant III: Nursing Management
321
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
321
Renal Corpuscle
7.0K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
7.0K
Acute Kidney Injury II: Pathophysiology
910
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
910
Nephrons
6.5K
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
6.5K


