导航支气管检查外周肺结节在现实世界中的内支气管超声波分期:哪些患者将受益?
Desi K M Ter Woerds1, Roel L J Verhoeven1, Ad F T M Verhagen2
1Department of Pulmonary Diseases, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Cancers
|May 28, 2025
概括
对于肺结节,如果[18F]FDG-PET或CT扫描显示没有淋巴结参与,则可能不需要Endobronchial超声波 (EBUS). 这可以帮助简化对接受导航支气管镜检查 (NB) 的患者的诊断.
科学领域:
- 肺部病理学 肺部病理学
- 胸部瘤学 胸部瘤学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 肺癌的诊断往往涉及到周围的肺结节.
- 导航支气管镜 (NB) 经常用于这些结节.
- 脑内支气管超声波 (EBUS) 通常与NB结合用于分期.
研究的目的:
- 为了评估EBUS在患者的附加值,请参考NB.
- 为了评估EBUS实用性与程序前[18F]FDG-PET和CT成像相结合.
- 为了确定成像是否可以安全地指导节点分期的EBUS省略.
主要方法:
- 连续接受NB治疗的患者的单中心研究.
- 对[18F]FDG-PET和对比度增强的胸部CT (ceCT) 报告对淋巴腺病的分析.
- 影像检测结果与EBUS和手术结果的相关性.
主要成果:
- 35%的患者在成像上呈阳性淋巴结;EBUS证实了其中8.4%的N+疾病.
- 手术揭示了隐藏的结节转移在3.1%的成像阴性淋巴结患者.
- 在403名患者中,EBUS在81.1%的患者中进行.
结论:
- 在患有外围肺结节的患者中,可以安全地省略EBUS,当[18F]FDG-PET或ceCT显示没有结节参与时.
- 术前成像可能会简化肺结节分期的诊断途径.
- 这种方法可以减少对特定患者群体的不必要程序.
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