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在患有严重COVID-19疾病的患者中侵袭性疹共感染:范围审查

Omar Esteban Valencia-Ledezma¹, María Del Rocío Reyes-Montes², Gustavo Acosta-Altamirano³

¹Departamento de Investigación, Hospital Regional de Alta Especialidad de Ixtapaluca, Servicios de Salud del Instituto Mexicano de Seguro Social para el Bienestar (IMSS-BIENESTAR), Ixtapaluca 56530, Mexico.

Pathogens (Basel, Switzerland)

|May 28, 2025

概括

在COVID-19患者中,侵袭性 кандидоз共感染率增加. 这种真菌共感染显著恶化了结果,包括更高的死亡率和更长的重症监护室停留时间.

科学领域:

传染性疾病传染性疾病
关键护理医学关键护理医学
菌类学菌类学是指菌类学.

背景情况:

随着COVID-19大流行,患者中的 кандидоз共感染病例显著增加.
侵袭性角膜炎是一种严重的威胁,尤其对重症患者来说.

研究的目的:

对严重的COVID-19患者的侵袭性 кандидоз共感染的科学证据进行范围审查.
分析SARS-CoV-2感染与侵入性真菌共感染之间的关联.

主要方法:

在主要在线数据库 (PubMed,Scopus等) 中进行系统搜索. 对于发表于2020年1月至2022年12月的研究.
根据PRISMA-ScR指南,选择了48篇关于侵入性角膜炎和COVID-19并发症的出版物,这些出版物遵循PRISMA-ScR指南.
分析了169,468名成年重症监护病房患者的数据.

主要成果:

大多数研究 (57%) 是观察性研究,43% 是系统性审查.
虫虫是占主导地位的物种 (75%),其他物种也被确定,包括Meyerozyma parapsilosis和Nakaseomyces glabratus.
在SARS-CoV-2感染和侵入性真菌共感染的发病率增加之间发现了显著的关联.

结论:

患有严重COVID-19的患者表现出更高的侵袭性 kandidasis 同感染的发病率.
这种共感染与增加的死亡率,疾病严重程度和长时间的重症监护病房住院有关.
真菌共感染是严重的COVID-19管理中的一个关键并发症.

关键词:

在 COVID-19 疫情中,在Candida albicans中使用.候选症候群病是一种候选症.共同感染是一种共感染.侵袭性角膜炎症是一种侵入性角膜炎症.

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