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用人工智能的力量改变药物基因组学和CRISPR基因编辑,用于精确医学

Amit Kumar Srivastav¹, Manoj Kumar Mishra², James W Lillard^1,3

¹Department of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, GA 30310, USA.

|May 28, 2025

概括

精准医学正在通过药物基因组学,人工智能 (AI) 和CRISPR基因编辑的整合而迅速发展. 这些技术通过分析DNA,优化治疗,精确编辑基因来改善患者的治疗结果,从而实现个性化治疗.

科学领域:

生物技术是生物技术.
基因组学就是基因组学.
计算生物学计算生物学

背景情况:

药物基因组学,人工智能 (AI) 和CRISPR基因编辑是精准医学的关键驱动力.
人工智能增强生物标志物发现和药物优化.
药物基因组学识别了影响药物反应的遗传变异,而CRISPR使精确的基因编辑成为可能.

研究的目的:

探索药物基因组学,人工智能和CRISPR在推进精准医学方面的协同效应.
审查有关这些融合技术的当前文献.

主要方法:

系统性文献审查,重点关注药物基因组学,人工智能和CRISPR应用.
分析它们在预测建模和基因编辑中的作用.

主要成果:

人工智能驱动的药物基因组学能够根据DNA进行个性化药物选择,减少副作用并提高疗效.
克里斯普技术促进了精确的基因修改,以改善各种疾病的治疗结果.
人工智能集成增强了CRISPR的特异性,并简化了基因组编辑应用程序,尽管存在诸如偏见和道德问题等挑战.

结论:

人工智能,药物基因组学和CRISPR的融合为个性化治疗干预提供了变革性的潜力.
临床翻译需要解决数据隐私问题,确保公平访问,并建立强大的法律框架.
未来的研究应该专注于改进CRISPR,增强药物基因组学中的AI,并为个性化医学制定伦理准则.

关键词:

基因编辑CRISPR基因编辑人工智能的人工智能是人工智能.遗传生物标志物遗传生物标志物药物基因组学药物基因组学精准医学是一门精准医学.

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