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Updated: Sep 20, 2025

Using Reverse Genetics to Manipulate the NSs Gene of the Rift Valley Fever Virus MP-12 Strain to Improve Vaccine Safety and Efficacy
09:13

Using Reverse Genetics to Manipulate the NSs Gene of the Rift Valley Fever Virus MP-12 Strain to Improve Vaccine Safety and Efficacy

Published on: November 1, 2011

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通过增强NS5B聚合酶功能,PKM2促进了古典猪瘟病毒的复制

Mengzhao Song1, Shanchuan Liu1, Yan Luo1

  • 1College of Veterinary Medicine, Northwest A&F University, Yangling 712100, China.

Viruses
|May 28, 2025
PubMed
概括

酸激酶M2 (PKM2) 通过与病毒NS5B蛋白相互作用,增强病毒RNA合成和传播,支持古典猪瘟病毒 (CSFV) 复制. 这项研究揭示了PKM2是关键的前病毒宿主因子.

关键词:
在NS5B中,它是NS5B.RdRp活动活动.经典猪瘟病毒 经典猪瘟病毒酸盐激酶M2的 pyruvate 激酶 M2 的 pyruvate 激酶 M2 的 pyruvate 激酶病毒感染 病毒感染

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