Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Vaccinations01:51

Vaccinations

45.4K
Overview
45.4K
Cross-reactivity00:42

Cross-reactivity

31.5K
Overview
31.5K
Development of Immunocompetence01:22

Development of Immunocompetence

463
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
463

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Optimizing dengue vaccination strategies.

PLoS medicine·2026
Same author

Country-level perspectives and priorities to guide the development of Invasive non-Typhoidal Salmonella (iNTS) vaccines: Insights from seven countries.

PLoS neglected tropical diseases·2026
Same author

The invasive non-typhoidal Salmonella vaccine landscape: Innovations and challenges ahead.

Vaccine·2026
Same author

Global disparities in the introduction, scale-up, and effectiveness evaluation of COVID-19 vaccines.

Nature communications·2025
Same author

WHO preferred product characteristics for bivalent Salmonella Typhi/Paratyphi A vaccine for comprehensive protection against enteric fever- key considerations and research gaps.

Gates open research·2025
Same author

Non-typhoidal Salmonella combination vaccines: clinical development plan and regulatory considerations.

Vaccine·2025

相关实验视频

Updated: Sep 20, 2025

Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection
06:00

Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection

Published on: January 26, 2024

1.5K

登革热疫苗开发和部署到常规免疫接种中

Annelies Wilder-Smith1, Thomas Cherian1, Joachim Hombach1

  • 1World Health Organization, CH-1211 Geneva, Switzerland.

Vaccines
|May 28, 2025
PubMed
概括

将像TAK-003这样的登革热疫苗纳入常规免疫接种中对于高负担地区至关重要. 策略包括基于学校的计划和社区参与,以打击不断增加的登革热病例.

科学领域:

  • * 热带医学 热带医学
  • * 疫苗学 疫苗学 疫苗学
  • * * 公共卫生 公共卫生

背景情况:

  • *登革热是一个日益严重的全球健康问题,尽管经过数十年的研究,疫苗的实施仍然有限.
  • *目前,只有两种登革热疫苗,即CYD-TDV (Dengvaxia) 和TAK-003 (Qdenga) 获得许可.
  • *高登革热发病率需要有效的疫苗接种策略.

研究的目的:

  • * 探索和概述将登革热疫苗纳入常规免疫计划的战略.
  • * 评估可用的登革热疫苗,特别是TAK-003.3的有效性和安全性考虑因素.
  • *为高负担地区的疫苗引入提供决策信息.

主要方法:

  • *对登革热疫苗和实施策略的现有文献的审查.
  • *分析TAK-003的疗效数据,包括针对病毒学证实的登革热和住院病例.
  • *审查世界卫生组织 (WHO) 关于疫苗增强疾病的建议和关切.

主要成果:

  • *TAK-003对确诊的登革热有61%的疗效,对住院有84%的疗效,但对血清阴性个体具有风险.
  • *世卫组织建议在高传播环境中,在没有预先查的情况下,有针对性地引入TAK-003.
关键词:
在 CYD-TDVV 中.在QdengaQdenga上这就是TAK-0033.沃尔巴基亚 (Wolbachia) 是一种植物.这是一种抗体依赖增强剂.登革热:登革热是指登革热的一种疾病.在mRNA疫苗的使用中.基于学校的课程是基于学校的课程.

更多相关视频

A Simple Flow Cytometry Based Assay to Determine In Vitro Antibody Dependent Enhancement of Dengue Virus Using Zika Virus Convalescent Serum
07:06

A Simple Flow Cytometry Based Assay to Determine In Vitro Antibody Dependent Enhancement of Dengue Virus Using Zika Virus Convalescent Serum

Published on: April 10, 2018

8.9K
Measuring Dengue Virus RNA in the Culture Supernatant of Infected Cells by Real-time Quantitative Polymerase Chain Reaction
08:36

Measuring Dengue Virus RNA in the Culture Supernatant of Infected Cells by Real-time Quantitative Polymerase Chain Reaction

Published on: November 1, 2018

32.1K

相关实验视频

Last Updated: Sep 20, 2025

Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection
06:00

Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection

Published on: January 26, 2024

1.5K
A Simple Flow Cytometry Based Assay to Determine In Vitro Antibody Dependent Enhancement of Dengue Virus Using Zika Virus Convalescent Serum
07:06

A Simple Flow Cytometry Based Assay to Determine In Vitro Antibody Dependent Enhancement of Dengue Virus Using Zika Virus Convalescent Serum

Published on: April 10, 2018

8.9K
Measuring Dengue Virus RNA in the Culture Supernatant of Infected Cells by Real-time Quantitative Polymerase Chain Reaction
08:36

Measuring Dengue Virus RNA in the Culture Supernatant of Infected Cells by Real-time Quantitative Polymerase Chain Reaction

Published on: November 1, 2018

32.1K
  • *正在进行后引入研究,以澄清长期的安全性和有效性.

    • 结论:

    • *优化目前登革热疫苗的使用对于减少疾病负担至关重要.
    • *有效的推广需要基于学校的计划,青少年健康整合和社区参与.
    • *将疫苗接种与载体控制相结合,对于对登革热发病率和死亡率的立即影响至关重要.