在接受抗风湿和抗抑郁药物治疗的母亲中,对母乳养建议的遵守率较低
Essi Whaites Heinonen1,2, Diana L Johnson1, Alec Todd1
1Center for Better Beginnings, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.
概括
服用慢性药物,特别是抗风湿药物 (ARM) 的母亲不太可能完全母乳养. 需要针对这些药物的母乳养母亲提供有针对性的支持和更多的安全数据.
科学领域:
- 生殖健康 生殖健康
- 药理学 药理学是指药理学的学科.
- 儿科 儿科 儿科
背景情况:
- 全球范围内建议在六个月内独家母乳养.
- 哺乳期间许多药物的安全数据有限.
- 在怀孕期间长期使用药物对母乳养决策提出了挑战.
研究的目的:
- 评估使用慢性药物的母亲开始和继续母乳养的可能性.
- 确定特定的药物类别是否会影响母乳养时间和补充剂.
- 为临床实践提供有关为患有慢性疾病的母亲提供母乳养支持的信息.
主要方法:
- 来自MotherToBaby队列的6383名孕妇的二次分析 (美国和加拿大,2010-2022年).
- 对抗风湿性药物 (ARM),SSRI和喘药物的药物持续使用者和停止使用者之间的母乳养结果的比较.
- 使用修改后的Poisson和Cox回归来计算调整后的风险和危险比率的统计分析.
主要成果:
- 使用ARM (持续使用和停止使用) 的母亲显著减少母乳养的可能性,更有可能补充,并且更有可能在六个月前停止使用.
- 持续使用的SSRI药物显示,母乳补充配方奶粉的可能性更高.
- 很大一部分参与者 (69.6%) 没有接触到研究药物.
结论:
- 慢性药物使用,特别是ARM,与母乳养率和持续时间的减少有关.
- 增强的哺乳支持对于管理慢性疾病的母亲至关重要.
- 需要进一步的研究来开发各种慢性药物的全面母乳养安全数据.
关键词:
抗抑郁药是一种抗抑郁药.抗风湿药物 抗风湿药物喘的药物 喘的药物母乳养 母乳养 哺乳哺乳的障碍 哺乳的障碍开始母乳养的开始疾病修饰性抗风湿药物 疾病修饰性抗风湿药物哺乳期 哺乳期 哺乳期预期的队列研究.选择性血清素再吸收抑制剂 选择性血清素再吸收抑制剂更多相关视频
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