耳鼻喉科患者报告结果测量的最小临床重要差异的可信性:一个范围审查
Maryann Zhao1,2, Lucy Xu3, Deborah Goss3
1Harvard Medical School, Boston, Massachusetts, USA.
概括
在耳鼻喉科中,确定患者报告的结果测量 (PROM) 的最小临床重要差异 (MCID) 是至关重要的. 然而,由于方法不一致,许多报告的MCID缺乏可信性,因此需要标准化的指导方针来提供可靠的临床解释.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 临床结果研究研究
- 健康测量健康测量
背景情况:
- 基于的方法对于在患者报告的结果测量 (PROM) 中建立最小临床重要差异 (MCID) 是至关重要的.
- 耳鼻喉科MCID确定现有的方法缺乏一致性,影响临床变化检测的可靠性.
- 评估这些MCID的可信度对于准确的患者状态评估至关重要.
研究的目的:
- 在耳鼻喉科中,批判性地评估患者报告结果措施 (PROM) 基于的临床重要差异最小值 (MCID) 的可信性.
- 为了确定当前MCID确定方法的不一致性.
- 为制定更严格和标准化的MCID计算方法提供信息.
主要方法:
- 从PubMed,Embase和Web of Science开始到2024年1月进行系统的文献搜索.
- 包括报告耳鼻喉科PROMs新型基MCIDs的研究.
- 评估MCID可信度使用五个标准仪器,重点关注点属性,相关性,样本大小和值意义.
主要成果:
- 在耳鼻喉学中发现的74个MCID中,只有25%被认为是可信的,48%的可信度很低.
- 在34%的病例中,-PROM相关性没有报告.
- 虽然70%使用了足够小和临床相关的差异,但整体可信度仍然很低,突出了方法上的差距.
结论:
- 对于耳鼻喉科中患者报告的结果测量 (PROM) 的有限数量的基于的临床重要差异 (MCID) 符合可信度标准.
- 在目前的MCIDs确定中发现了重大不一致性和方法缺陷.
- 在定义MCID方面迫切需要加强严格性和标准化指导方针,以确保临床相关性和患者益处.
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