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在中风后和多发性硬化症患者中使用肉毒素治疗性治疗:回顾性",现实世界"多中心研究

Calogera Butera¹, Marcello Esposito², Trinchillo Assunta³

¹Neurophysiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.

NeuroRehabilitation

|May 28, 2025

概括

毒素-A (BoNT-A) 有效地管理中风和多发性硬化症患者在现实环境中的性. 大多数人对长期的BoNT-A治疗对各种性原因表示满意.

科学领域:

神经学神经学
康复医学康复医学康复医学
药理学药理学是指药理学的学科.

背景情况:

对于多发性硬化症 (MS) 的肉毒素-A (BoNT-A) 存在有限的现实世界数据,尽管有强有力的证据表明中风后.
这项研究解决了临床实践中关于BoNT-A在各种性病因中的缺乏信息的问题.

研究的目的:

记录BoNT-A在治疗性的现实应用.
专注于治疗中风和多发性硬化症导致的性.

主要方法:

采用了一种非干预性,回顾性研究设计.
分析了来自149名成年患者的数据,这些患者在2008年至2018年期间在意大利三个中心接受了至少三次BoNT-A注射周期.
患者有任何病因的上肢和/或下肢性.

主要成果:

分析包括67名中风后,47名多发性硬化和35名其他病因患者.
平均治疗持续时间为54.9个月 (中风后) 和41.9个月 (MS).
观察到的BoNT-A剂量往往低于批准的剂量,MS和中风后组之间有不同的肌肉治疗模式;然而,患者满意度在病因方面很高.

结论:

这项研究提供了对BoNT-A用于性管理的现实世界视角.
这些发现支持BoNT-A治疗焦点的有效性和患者满意度,不论其根本原因是什么.
这些数据强调了BoNT-A在超出中风指标的长期性护理中的实用性.

关键词:

肉毒毒素A是一种肉毒毒素.多发性硬化症多发性硬化症观察性研究是一种观察性研究.康复康复康复康复康复康复性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性,性等.一次性中风中风中风中风中风治疗药物治疗药物

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