根据贝塞斯达系统分类的儿科甲状腺结节的恶性风险
Katia Averbukh-Oren1,2, Sabri El-Saied1,2, Roy Hod3,4
1Department of Otorhinolaryngology and Head and Neck Surgery, Soroka University Medical Center, Be'er Sheva, Israel.
Clinical endocrinology
|May 28, 2025
概括
儿童甲状腺结节在所有贝塞斯达类别的恶性病发病率都高于成年人. 这表明需要在怀疑甲状腺结节的儿童中进行更密集的评估.
科学领域:
- 内分泌学 在内分泌学.
- 儿科瘤学 儿科瘤学
- 细胞病理学 细胞病理学
背景情况:
- 甲状腺结节在儿童中较少见,但患恶性瘤的风险更高.
- 贝塞斯达系统报告甲状腺细胞病理学将结节分类,以预测恶性瘤风险.
- 这项研究评估了使用贝塞斯达系统的儿科甲状腺结节的恶性潜力.
研究的目的:
- 用贝塞斯达系统估计儿童甲状腺结节的恶性潜力.
- 为了比较小儿甲状腺结节中的恶性瘤率与成人数据和现有指导方针.
主要方法:
- 对121名儿童患者 (≤19岁) 的回顾性研究,这些患者在精细针吸收 (FNA) 后接受了甲状腺手术.
- 用贝塞斯达分类系统对结节进行了分类.
- 计算了每个类别的恶性病发率,并与最终的病理学结果进行了比较.
主要成果:
- 在121个结节中,66个 (54.5%) 是恶性.
- 恶性瘤的风险包括:B2 (24%),B3 (52.6%),B4 (58.8%) 和B5-B6 (100%).
- 与成人数据相比,所有贝塞斯达类别的儿科患者的恶性病发病率更高.
结论:
- 在所有贝塞斯达类别中,儿童甲状腺结节的恶性瘤发病率高于成人.
- 在儿童中观察到的恶性瘤发病率超过了之前在可比儿科研究中报告的情况.
- 对于怀疑甲状腺结节的儿科患者,特别是那些具有临床或超声波特征的儿科患者,建议采用更密集的评估方法.
更多相关视频
相关概念视频
The Thyroid Gland
4.4K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
4.4K
Functions of Thyroid Hormones
3.2K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
3.2K
Pulmonary Tuberculosis III
459
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
459


