怀孕期间体重变化和不良出生结果:使用巴西常规基于登记册的链接数据的队列研究
Aline S Rocha1,2, Thais Rangel Bousquet Carrilho3, Priscila R F Costa1,2
1Center of Data and Knowledge Integration for Health (CIDACS), Oswaldo Cruz Foundation, Salvador, Brazil.
Maternal & child nutrition
|May 28, 2025
概括
怀孕期间的体重变化会影响随后的怀孕结果. 在怀孕期间体重增加或减轻会增加早产和巨的风险,这凸显了对母亲体重管理的需要.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 公共卫生 公共卫生
背景情况:
- 怀孕期间体重变化 (IPWC) 对不良分娩结果的影响尚不清楚,关于早产的数据相互矛盾,以及低出生体重 (LBW) 或巨的证据有限,特别是在低收入和中等收入国家.
- 了解IPWC对于改善全球母亲和婴儿健康至关重要.
研究的目的:
- 评估妊娠间体重变化 (IPWC) 与随后怀孕中不良分娩结果之间的关联.
- 为了研究怀孕之间的体重变化对早产,LBW和巨的影响.
主要方法:
- 一项基于人口的纵向研究,使用链接的巴西注册数据 (2008-2015).
- 分析了来自7785名多夫妇妇女的15570名活产婴儿.
- 后勤和多项后勤回归来评估IPWC类别 (BMI单位变化,BMI类别变化,体重百分比变化) 和不良出生结果之间的关联.
主要成果:
- 在怀孕期间降低BMI的女性,早产的几率增加了 (OR 1.27).
- 与维持BMI的女性相比,增加BMI≥4个单位的女性患大症的几率增加了 (OR1.60).
- 使用BMI类别和体重百分比变化发现了类似的关联.
结论:
- 怀孕期间的体重变化与随后的怀孕中新生儿成熟度和体型的改变有关.
- 在怀孕期间的孕产妇体重管理对于改善分娩结果至关重要.
- 需要进一步的实验研究来证实这些发现并指导干预措施.
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