患者特异性因素,患者偏好和结节大小作为高风险不确定的甲状腺结节的初始手术中的含义
Lorenzo Scappaticcio1,2, Nicole Di Martino2, Pamela Ferrazzano2
1Unit of Endocrinology and Metabolic Diseases, AOU University of Campania "Luigi Vanvitelli", Naples, Italy.
Endocrine
|May 28, 2025
概括
全甲状腺切除术 (TT) 是高风险的不确定性 (TIR3B) 甲状腺结节的常见病例. 较大的结节大小增加了卵泡甲状腺癌 (FTC) 的风险及其侵略性,有助于进行手术的决定.
科学领域:
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
- 细胞病理学 细胞病理学
背景情况:
- 被归类为高风险不确定性 (TIR3B) 的甲状腺结节是一个诊断挑战.
- 确定TIR3B结节的最佳手术方法对于患者的治疗结果至关重要.
研究的目的:
- 为了评估TIR3B甲状腺结节的全甲状腺切除术 (TT) 的频率.
- 为了确定与皮囊性甲状腺癌 (FTC) 中的TT相关的患者特异性因素 (PSF).
- 评估结核大小作为恶性瘤风险和FTC攻击性的预测指标.
主要方法:
- 对112个TIR3B甲状腺结节 (56个FTC,56个卵泡腺瘤) 的回顾性分析.
- 从2018年3月至2024年12月间经过手术的成年患者收集的数据.
- 统计分析以关联PSF,结节大小和FTC特征.
主要成果:
- 在83%的病例中进行了全甲状腺切除术 (TT).
- 患者特异性因素 (PSF) 并没有显著预测TT.
- 结节大小 (3040毫米) 增加了FTC的风险 (OR 2.0,p=0.022).
- 较大的FTC表现出越来越多的侵略性.
结论:
- 全甲状腺切除术 (TT) 是TIR3B结节的主要初始手术.
- 结节大小是TIR3B结节手术决策的重要因素.
- 患者的偏好和PSF应该与结节大小一起考虑.
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