脑静脉血栓症中预测 - 一个回顾性单中心观察性研究
Patrícia Faustino1, Diana Melancia2,3
1Neurology Department,Hospital de São José, Unidade Local de Saúde São José, R. José António Serrano, 1150-199, Lisboa, Portugal. patriciarfaustino@gmail.com.
大约三分之一的脑静脉血栓塞 (CVT) 患者经历了发作. 出血病变和上纵侧鼻腔或皮层静脉的参与是CVT中急性症状 (AS) 的关键预测因素.
科学领域:
- 神经学 神经学
- 脑卒中医学 脑卒中医学
- 神经成像是一种神经成像.
背景情况:
- 大脑静脉血栓形成 (CVT) 是一种罕见的中风原因,常常伴有发作.
- 在CVT中确定急性症状性发作 (AS) 的预测因子对于患者管理至关重要.
- 之前的研究表明,临床和放射学因素在CVT中影响AS风险.
研究的目的:
- 确定脑静脉血栓症 (CVT) 患者急性症状性发作 (AS) 的临床和成像预测因素.
主要方法:
- 在2011-2022年期间入院的156名CVT患者的回顾性队列研究.
- 使用后勤二进制回归和多变量分析来比较临床和放射性特征.
- 主要结局是AS的发生.
主要成果:
- 33.3%的患者经历了发作,其中30.1%患有AS.
- 焦点征兆,上纵侧鼻 (SLS) 或皮层静脉干扰,出血性病变,,以及额叶/叶病变与AS风险增加有关.
- 多变量分析证实了SLS参与 (OR 6.06),皮质静脉参与 (OR 2.76) 和出血病变 (OR 3.47) 是重要的预测因素.
结论:
- 在CVT患者中,发作很常见,主要是AS.
- 出血性病变,SLS和皮层静脉干扰与AS风险密切相关.
- 这些发现提高了人们对CVT急性阶段发作风险的认识.
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