在密歇根州高风险成年人中,同行支持干预预防自杀:一项随机临床试验
Paul N Pfeiffer1,2, Kristen M Abraham3, Adrienne Lapidos1
1Department of Psychiatry, University of Michigan Medical School, Ann Arbor.
JAMA network open
|May 28, 2025
概括
价值生活同行 (PREVAIL) 干预措施并没有显著减少因自杀风险住院的成年人的自杀未遂或自杀念头. 需要进一步的研究来探索它的有效性.
科学领域:
- 精神病学和行为科学
- 公共卫生 公共卫生
- 临床心理学 临床心理学
背景情况:
- 自杀在美国仍然是一个重大的公共卫生问题,自杀率持续上升.
- 针对人际关系风险因素的创新干预措施对于预防自杀至关重要.
- 住院后的同行支持可能提供一种新的方法来减少自杀企图和想法.
研究的目的:
- 评估同龄人为有价值的生活 (PREVAIL) 干预措施在减少自杀企图和自杀念头方面的有效性.
- 为了比较医院后同行支持计划与高风险精神病患者的增强常规护理.
主要方法:
- 一个单面罩的随机临床试验,涉及三家密歇根医院的成年精神病患者.
- 参与者接受了PREVAIL干预 (退院后3个月的同行支持) 加上增强的常规护理或单独增强的常规护理.
- 自杀企图和自杀想法在随机化后的3个月和6个月被评估,使用标准化尺度.
主要成果:
- 在减少自杀企图或自杀念头方面,在PREVAIL手臂和增强的常规护理之间没有发现统计学上显著的差异.
- 后期分析显示,研究部门和COVID-19大流行病在自杀意念得分之间存在显著的相互作用.
- 在初级分析中,PREVAIL干预措施没有显著减少自杀企图或自杀想法.
结论:
- 同行提供的PREVAIL干预,在出院后长达3个月,与增强的常规护理相比,没有显著减少自杀企图或自杀想法.
- 这些发现表明,这种特定的同行支持模式可能不足以作为该群体的独立干预.
- 进一步调查定制同行支持干预措施,并考虑流行病等背景因素是有必要的.
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