气管支气管置换:一个系统的审查
Emmanuel Martinod1,2,3, Dana M Radu1,2,3, Ilaria Onorati1,2,3,4
1Chirurgie Thoracique et Vasculaire, Hôpital Avicenne, Hôpitaux Universitaires Paris Seine-Saint-Denis, Assistance Publique-Hôpitaux de Paris (AP-HP), Bobigny, France.
JAMA surgery
|May 28, 2025
概括
气管支气管替代主要用于广泛的癌症,冷保存的大动脉全移植显示出有希望的结果. 结果与其他胸部手术相似,但长期生存取决于潜在的疾病.
科学领域:
- 胸部外科手术 胸部外科手术
- 手术瘤学手术瘤学
- 再生医学是一种再生医学.
背景情况:
- 气管支气管置换带来了重大的手术和生物挑战.
- 几十年的研究已经探索了各种实验和临床方法.
研究的目的:
- 为了提供一个全面的回顾,目前的状态的气管支气管替换.
- 检查指示,技术和患者的结果.
主要方法:
- 在2024年7月1日进行了一项系统的文献审查.
- 搜索的数据库包括PubMed,Embase和Cochrane控制试验中央注册表.
- 在研究选择和报告时遵循了PRISMA指南.
主要成果:
- 包括126个出版物,其中大多数是案例报告/系列.
- 自2022年以来,冷保存的大动脉全移植已经成为一种广泛使用的方法.
- 适应症包括瘤 (78.8%) 和良性狭窄症 (21.2%).
- 30天死亡率和发病率分别为2.9%和22.9%.
结论:
- 广泛的恶性病变是气管支气管支气管替代的主要指示.
- 冷保存的大动脉全移植是唯一科学评估的技术.
- 结果与其他主要胸部手术相似,长期存活率受到主要疾病的影响.
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