12个新生儿网络中的输血实践:我们是否更接近采用限制性输血方法?
Gil Klinger1,2, Kjell Helenius3, Maximo Vento4
1Department of Neonatal Intensive Care, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.
Neonatology
|May 28, 2025
概括
在全球范围内,对早产婴儿输血的做法各不相同. 大多数新生儿重症监护病房 (NICU) 现在都采用了限制性方法,与最近关于管理早产婴儿的证据保持一致.
科学领域:
- 新生儿医学 新生儿医学
- 儿科血液学 儿科血液学
- 临床实践指南 临床实践指南
背景情况:
- 新出现的证据支持对早产婴儿输血的限制性方法.
- 这项研究调查了当前对非常早产新生儿的输血实践.
研究的目的:
- 为了调查早产新生儿 (<29周怀孕) 的输血实践.
- 评估12个国际新生儿网络 (iNeo) 的实践.
主要方法:
- 在2023年全球608个新生儿重症监护室 (NICU) 分发了一项在线调查.
- 对早产婴儿的四种不同的临床情景进行了实践调查.
- 场景包括不同程度的呼吸支和产后年龄.
主要成果:
- 382个NICU (63%) 反应,显示了输血实践的显著差异.
- 限制性方法 (血红素≤35%或≤30%) 是常见的呼吸婴儿.
- 对于稳定的婴儿,值通常为血红素≤30% (非侵入性支持) 或≤25% (没有支持).
结论:
- 各国之间和网络内部的输血实践存在实质性的差异.
- 超过三分之二的NICU采用了限制性输血方法.
- 需要进一步的研究来使实践与意图保持一致,并评估它们对结果的影响.
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