评估黑人和白人患者之间静脉血栓栓塞率差异背后的因素
Mary S Lin1, Shalini Sahoo1, Hilary Hayssen1
1Department of Surgery, University of Maryland, Baltimore, MD.
概括
黑人种族是医院相关静脉血栓塞栓症 (VTE) 的独立风险因素. 较低的血红蛋白水平可能导致黑人患者的静脉瘤发作率较高,这表明潜在的临床解释.
科学领域:
- 临床医学 临床医学
- 血液学 血液学 血液学
- 流行病学 流行病学
背景情况:
- 在美国,与医院相关的静脉血栓栓塞 (VTE) 发生率在黑人患者中高于白人患者.
- 这种VTE比率种族差异的根本原因尚不清楚.
研究的目的:
- 评估导致黑人和白人患者静脉瘤发病率差异的临床因素.
- 调查种族和VTE之间的关联,调整潜在的混因素.
主要方法:
- 对一大批退伍军人事务医院住院患者 (2016-2021) 的全国性队列进行分析.
- 黑人和白人患者入院后90天内静脉瘤发作率的比较.
- 开发后勤回归模型来评估种族,混因素和VTE之间的关系.
主要成果:
- 该研究包括142,456名患者 (28.5%黑人,71.5%白人).
- 总体VTE发病率为2.4%,黑人患者 (2.7%) 和白人患者 (2.3%) 的发病率更高.
- 在调整了社会剥夺,血型和手术后,黑人种族仍然与增加的VTE几率 (OR,1.06-1.17) 有关. 调整血红蛋白降低了这种关联.
结论:
- 黑人种族是VTE的重要风险因素,独立于社会决定因素和外科手术因素.
- 血红蛋白水平可能会调节黑人种族与VTE之间的关联,表明潜在的临床病因.
- 对血红蛋白在VTE差异中的作用进行进一步的研究是有必要的.
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