相关实验视频
Updated: Sep 20, 2025

08:52
Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
Published on: February 22, 2019
10.8K
儿科帕帕图西斯的临床特征:一个单中心病例控制研究
Ken Okamoto1, Takanori Funaki2, Satsuki Kidokoro3
1Center for Postgraduate Education and Training, National Center for Child Health and Development (NCCHD), Tokyo, Japan.
概括
在日本,儿童的咳,通常是轻微的和共传染性,是未被认可的. 需要进一步的监测,以了解其疾病负担,并指导对这种Bordetella parapertussis感染的管理策略.
科学领域:
- 儿童传染病 儿童传染病
- 细菌学 细菌学是一门学科.
- 流行病学 流行病学
背景情况:
- 由Bordetella parapertussis引起的百日咳在临床上与百日咳相似,但在日本没有得到充分的认可.
- 在日本,它不是一个必须报告的疾病,这限制了监测和了解其流行程度和影响.
研究的目的:
- 阐明在日本儿童中发生的帕帕图西斯的临床和流行病学特征.
- 为了确定检测率,同时感染模式和Bordetella parapertussis的临床表现.
主要方法:
- 东京一家儿科中心的回顾性研究 (2020年10月至2023年11月).
- 包括18岁以下的儿童通过FilmArray®呼吸系统面板2.1检测出Bordetella parapertussis的阳性.
- 分析了人口统计,临床和实验室数据,比较单一和并发感染.
主要成果:
- 在0.36%的测试中 (45/11,384) 检测到Bordetella parapertussis,检测率将在2023年增加.
- 大多数病例 (82.2%) 涉及并发感染,主要是人类鼻病毒/肠病毒.
- 症状一般是轻微的 (咳71.1%,发烧46.6%),没有严重的结果需要机械通风或重症监护.
结论:
- 日本儿童的咳通常表现出轻微的症状,并且经常与其他呼吸道病原体同时发生.
- 与同时感染的患者相比,单感染患者的淋巴细胞数量较低.
- 缺乏全国范围的监测,阻碍了对咳负担的准确评估和制定有效的管理策略.
相关概念视频
Single Nucleotide Polymorphisms-SNPs
16.0K
A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
16.0K
Pneumonia I: Introduction
345
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
345
Pneumonia II: Pathophysiology
622
The pathophysiology of pneumonia involves the following steps:
622
Principles of Disease Surveillance
190
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
190
Sputum Studies II: Culture and Sensitivity
634
Description
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
634
Pulmonary Tuberculosis IV
212
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
212

