乳制品摄入量对循环脂肪酸的影响和与血压的关联:一个随机交叉试验
Hana Arghavani1, Jean-François Bilodeau1, Iwona Rudkowska2
1Faculty of Medicine, Laval University, Quebec, Quebec, G1V 0A6, Canada; Endocrinology and Nephrology Research axis, CHU of Quebec-Laval University, Quebec, Quebec, G1V 4G2, Canada.
高乳制品摄入量会增加特定脂肪酸 (FA),如15:0和17:0. 这些食脂肪酸与血压有不同的关联,其中17:0与透气血压相反相关.
科学领域:
- 营养科学 营养科学
- 心血管健康 心血管健康
- 代谢学 代谢学 代谢学
背景情况:
- 饮食中摄入乳制品是一种常见的营养策略.
- 特定的循环脂肪酸 (FA) 可能会影响血压 (BP).
- 了解乳制品FA和BP之间的关系对于心血管健康至关重要.
研究的目的:
- 研究高乳制品 (HD) 与充足乳制品 (AD) 饮食对循环脂肪酸的影响.
- 检查特定FA和血压参数之间的关联.
- 探索改善心血管健康的饮食策略.
主要方法:
- 随机交叉临床试验与27名参与者.
- 对于HD和AD饮食,有六周的干预期,分别有洗期.
- 通过气相色谱分析与脂结合的血脂肪酸;测量血压和动脉硬度.
主要成果:
- 高乳制品摄入量与达基酸 (15:0) 和达基酸 (17:0) 的水平增加有关.
- 棕酸 (16:0) 和总和脂肪酸显示出与静缩 (SBP) 和静缩 (DBP) 血压的积极关联.
- 乙甲酸 (17:0) 显示与心压血压有相反的关联.
结论:
- 高乳制品消费会改变循环脂肪酸概况,特别是增加15:0和17:0.
- 特定的脂肪酸,如17:0和16:0,与血压成分有明显的关联.
- 专注于特定FA的饮食干预措施有可能改善心血管健康.
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