蒙古传统医学Ga-Mu-Zhu-Er的多元件分析使用诱导合等离子体质谱法
Qin Na1, Gu-Leng Amu2, Li Mei1
1College of Mongolian Medicine, Inner Mongolia Medical University, Hohhot, China.
The Journal of veterinary medical science
|May 28, 2025
概括
这项研究验证了一种分析传统蒙古医学Ga-Mu-Zhu-Er (GMZE) 中30个元素的方法. 感应合血质谱法 (ICP-MS) 方法可靠用于草药中微量元素的常规量化.
科学领域:
- 分析化学 分析化学
- 药理学是指药理学,即药理学是指药理学.
- 环境科学 环境科学
背景情况:
- 由于对重金属污染的担忧,传统药物的国际贸易受到阻碍.
- 传统蒙古医学Ga-Mu-Zhu-Er (GMZE) 含有多种化学和无机元素.
- 准确的元素分析对于确保草药的安全性和质量至关重要.
研究的目的:
- 在GMZE中验证30个元素的同时分析方法.
- 建立一个可靠的方法,用于GMZE和类似的草药产品的常规质量控制.
主要方法:
- 密闭容器微波消化使用缩的酸.
- 诱导合等离子体质谱 (ICP-MS) 用于元素量化.
- 分析参数的验证,包括线性,特异性,LOD,LOQ,精度和准确性.
主要成果:
- 通过微波消化实现了高回收率 (91.9-107.7%).
- 低检测极限 (LOD:0.00015-0.21μg/L) 和量化极限 (LOQ:0.00046-0.64μg/L) 是一个极限.
- 在GMZE样本中, (Ca), (As) 和 (Hg) 是最丰富的; (Be) 和银 (Ag) 是最少的.
结论:
- 开发的ICP-MS方法简单,快速和可靠,用于分析GMZE中的30种必需和非必需的微量元素.
- 这种方法支持传统蒙古医学,传统中国医学和食补充剂的常规质量控制.
- 经过验证的方法确保了国际草药贸易中可接受的分析性能.
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