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Updated: Sep 20, 2025

Inner Mitochondrial Membrane Sensitivity to Na+ Reveals Partially Segmented Functional CoQ Pools
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Published on: July 20, 2022

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CoQ 不平衡驱动反向电子运输以破坏肝脏代谢

Renata L S Goncalves1, Zeqiu Branden Wang1, Jillian K Riveros1

  • 1Department of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, MA, USA.

Nature
|May 28, 2025
PubMed
概括

线粒体反应性氧物种 (mROS) 的产生与肥胖有关. 失效的辅酶Q (CoQ) 合成增加了CoQH2/CoQ比率,通过反向电子运输驱动mROS,这对代谢健康至关重要.

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