通过深度学习进行增强的盆腔CT细分:关于损失功能影响的研究
Elnaz Ghaedi1, Ali Asadi1, Seyed Abolfazl Hosseini2
1Department of Energy Engineering, Sharif University of Technology, Tehran, 8639-11365, Iran.
Journal of imaging informatics in medicine
|May 28, 2025
概括
卷积神经网络 (CNN) 在盆腔CT扫描中自动化风险器官 (OAR) 分段,改善放射治疗计划. SegResNet模型实现了高精度,为手动划分提供了有效的替代方案.
科学领域:
- 医疗成像医学成像
- 医疗保健中的人工智能
- 放射治疗规划 放射治疗规划
背景情况:
- 在用于放射治疗计划的盆腔CT图像中,手动对有风险的器官进行细分 (OAR) 是耗时的,容易引起观察者间的变化.
- 准确的OAR划分对于有效的放射治疗规划至关重要,尽量减少对健康组织的剂量,同时最大限度地提高瘤覆盖率.
研究的目的:
- 评估各种卷积神经网络 (CNN) 架构在盆腔CT图像中自动化OAR细分的有效性.
- 将U-Net,ResU-Net,SegResNet和Attention U-Net模型的性能与专家手动细分进行比较.
- 研究不同损失函数对包括膀,前列腺,直肠和股骨头在内的OAR细分精度的影响.
主要方法:
- 使用MONAI框架实现和比较U-Net,ResU-Net,SegResNet和注意力U-Net模型.
- 关于盆腔CT数据集的培训和验证,包括240名前列腺细分患者和220名其他OAR患者.
- 使用子相似系数 (DSC),贾卡德指数 (JI) 和第95百分点豪斯多夫距离 (95thHD) 的性能评估.
主要成果:
- 在所有OAR中,SegResNet表现出优异的性能,达到高的DSC值 (例如,膀0.951,前列腺0.829,左侧FH0.979).
- 注意U-Net也显示出强的结果,特别是在膀和直肠细分方面.
- 子损失函数在OAR中为SegResNet提供了最佳或同等的性能,DiceCE稍微改善了前列腺细分 (DSC=0.845).
结论:
- 先进的CNN,特别是SegResNet,为骨盆CT中的OAR细分提供了可靠和高效的自动化解决方案.
- 优化的CNN模型和损失函数可以显著提高放射治疗规划的精度和效率.
- 自动化细分有望减少手工工作量,提高临床放射治疗工作流程的一致性.
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