怀孕期间母亲吸烟与后代牙发育之间的关联:系统性审查
Harry Tiernan1, Muhammad Masud1, Sawyer Lange1
1The University of Sydney School of Dentistry, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.
Evidence-based dentistry
|May 28, 2025
概括
孕妇在怀孕期间吸烟 (MSDP) 可能会影响后代的牙发育,可能会增加牙缺陷和牙缺失的风险. 然而,证据质量较低,需要进一步研究才能得出最终结论.
科学领域:
- 牙科发展 牙科发展
- 公共卫生 公共卫生
- 生殖健康 生殖健康
背景情况:
- 怀孕期间母亲吸烟 (MSDP) 是一个已知的不良分娩结果的风险因素.
- MSDP对后代牙发育的具体影响需要进一步阐明.
- 现有的文献提出了关于MSDP和牙异常之间的关联的各种发现.
研究的目的:
- 系统地审查和综合当前关于母亲在怀孕期间吸烟对后代牙发育的影响的文献.
- 确定可能与MSDP相关的特定牙科疾病.
- 评估有关MSDP和牙科结果的证据质量.
主要方法:
- 在六个数据库 (MEDLINE,Embase,CINAHL,Scopus,Web of Science,MIC) 进行的系统文献搜索于2024年7月进行.
- 纳入标准集中在研究MSDP对后代牙状况的影响的研究上.
- 使用纽卡斯尔-太华尺度 (NOS) 评估的方法质量和使用GRADE的证据质量.
主要成果:
- 审查了17篇文章,检查了诸如牙切口低矿化 (MIH),牙缺陷,牙缺失,牙喷发和短根异常等结果.
- 大多数研究 (10/17) 显示了良好的方法质量,但整体证据质量对于大多数结果低至非常低.
- 大多数研究表明MSDP与牙缺陷,缺失牙和短根异常之间存在关联;与MIH的联系是不一致的,并且没有发现与牙喷发的明确联系.
结论:
- 怀孕期间母亲吸烟与某些后代牙发育条件之间存在潜在的联系.
- 目前的证据受到低质量和不一致性的限制,阻止了最终的结论.
- 高质量的研究对于建立对MSDP对牙发育影响的清晰理解至关重要.
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