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Updated: Sep 20, 2025

A Real-time Potency Assay for Chimeric Antigen Receptor T Cells Targeting Solid and Hematological Cancer Cells
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T细胞受体模仿CAR T细胞向甲素G信号

Jun Yan1, Chunhua Shi1, Guojun Yang1

  • 1Oncology Research for Biologics and Immunotherapy Translation (ORBIT), University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Leukemia
|May 28, 2025
PubMed
概括

研究人员确定了一个新的免疫治疗点,CG1,用于急性髓性白血病 (AML) 和慢性髓性白血病 (CML) 等髓性白血病. 针对CG1的化学抗原受体 (CAR) T细胞表现出强大的抗白血病活性,而不会伤害正常血细胞.

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