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Updated: Jun 23, 2026

Establishment of Epstein-Barr Virus Growth-transformed Lymphoblastoid Cell Lines
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使用初级B细胞和EBV-immortalizedB细胞参考基因组定义儿科和青少年B细胞的三维色素结构

Kaiyu Jiang1,2, Yao Fu3, Jennifer A Kelly3

  • 1Department of Pediatrics, Clinical and Translational Research Center, Jacobs School of Medicine and Biomedical Sciences, University of Buffalo, 875 Ellicott St, Buffalo, NY, 14203, USA.

BMC medical genomics
|May 28, 2025
PubMed
概括

儿科B细胞的3D基因组结构与成人细胞和细胞系非常相匹配,甚至在自身免疫性疾病风险基因周围. 这表明成人数据足以研究儿科自身免疫性疾病.

关键词:
B 细胞 B 细胞 B 细胞染色体的可访问性 染色体的可访问性染色体的形状是如何形成的青春期关节炎是一种关节炎.儿科自身免疫性疾病儿童自身免疫性疾病系统性狼是一种系统性狼.1 型糖尿病 1 型糖尿病

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