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Updated: Sep 20, 2025

The Use of Reverse Phase Protein Arrays RPPA to Explore Protein Expression Variation within Individual Renal Cell Cancers

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Published on: January 22, 2013

基于临床和蛋白质基的综合模型用于pRCC的诊断和预后预测

Zeya Xu¹, Linhui Zhang^1,2, Jiacheng Lyu¹

¹Clinical Research Center for Cell-based Immunotherapy of Shanghai Pudong Hospital, Fudan University Pudong Medical Center, State Key Laboratory of Genetics and Development of Complex Phenotypes, School of Life Sciences, Human Phenome Institute, Department of Urology, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, 200433, China.

Journal of hematology & oncology

|May 28, 2025

概括

这项研究开发了血蛋白质组模型,以准确诊断癌亚型和状细胞癌 (pRCC) 阶段. 这些模型为改善PRCC诊断和进展监测提供了非侵入性工具.

科学领域:

发现生物标志物的发现.
蛋白质组学是指蛋白质组学.
细胞癌研究细胞癌研究

背景情况:

乳头性细胞癌 (pRCC) 是一种异质的非清晰细胞亚型,预后不佳.
由于其发病率较低,对于pRCC存在有限的研究和非侵入性生物标志物.
pRCC通常被错误分类,突出了需要准确的诊断工具的需要.

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