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Updated: Sep 20, 2025

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure
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不同MET瘤改变对I型和II型MET抑制剂的反应性

Yonina R Murciano-Goroff1, Valentina Foglizzo2,3, Jason Chang4

  • 1Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

Clinical and translational medicine
|May 29, 2025
PubMed
概括

在有固体瘤的患者中发现了新的MET耐药突变. 二型氨酸激酶抑制剂 (TKIs) 对这些突变显示出有效性,指导针对MET改变癌症的向治疗.

关键词:
在MET中,MET是MET.对向治疗的耐药性类型I和类型II的技术知识产权.

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