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Updated: Jan 18, 2026

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
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对于罕见疾病临床试验的贝叶斯序列决策

Yuan Gao1, Jianling Bai1, Feng Chen1

  • 1Department of Biostatistics, School of Public Heath, Nanjing Medical University, Nanjing, China.

Technology and health care : official journal of the European Society for Engineering and Medicine
|May 29, 2025
PubMed
概括

这项研究引入了贝叶斯对罕见疾病临床试验的序列设计. 它允许更早地停止对优越性或徒劳性的试验,节省时间,成本,并防止患者暴露在无效治疗中.

关键词:
贝叶斯因子是一个贝叶斯因子.贝叶斯因子设计分析 设计分析贝叶斯的顺序决策是贝叶斯式的.序列贝叶斯因子测试测试罕见疾病 临床试验 罕见疾病 临床试验

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