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Updated: Sep 20, 2025

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在小乳酸中1型铜中心的轴联体突变的意想不到的影响:基于结构的分析和工程来增加减少潜力和活性

Jing-Xiang Wang1, Avery C Vilbert2, Lucas H Williams3

  • 1Department of Chemistry, The University of Texas at Austin 105 East 24th Street Austin TX 78712 USA yi.lu@utexas.edu.

Chemical science
|May 29, 2025
PubMed
概括

多铜氧化酶中的1型铜 (T1Cu) 中心的蛋白质工程是复杂的. 小乳糖酶 (SLAC) 的新突变成功调整了T1Cu的降解潜力和活性,用于增强电子转移应用.

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